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Anti-tnf alpha Antibody (CAT#: MOM-18034)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Recombinant Anti-Human tnf alpha Antibody MOM-18034 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant Humanized (from mouse) Antibody binds selectively to Human TNF alpha, expressed in Chinese Hamster Ovary cells(CHO)
  • Target
  • TNF alpha
  • Type
  • Humanized(from mouse) IgG1
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in FuncS, IF, Neut, ELISA, FC, IP, ICC and most other immunological methods.
  • Specific Activity
  • Tested positive against native antigen.
  • Predicted N terminal
  • H chain: EVQLVES; L Chain: DIQMTQS
  • Purity
  • Purity >95% by SDS-PAGE.
  • Storage
  • Store at -20°C. Avoid multiple freeze/thaw cycles.

BACKGROUND

  • Antigen Description
  • Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation.
  • Function
  • cytokine activity; identical protein binding; protease binding; protein binding; transcription regulatory region DNA binding; tumor necrosis factor receptor binding
  • Synonyms
  • DIF; TNFA; TNFSF2; TNF-alpha; tumor necrosis factor; APC1 protein; Cachectin; tumor necrosis factor-alpha; TNF, macrophage-derived; Differentiation inducing factor; Macrophage cytotoxic factor ; MCF; Necrosin; TNFalpha; TNF Monocyte Derived; TNF Superfamily Member 2; TNF superfamily, member 2; TNF, monocyte derived; TNFA; Tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor; Tumor necrosis factor, soluble form; Tumour Necrosis Factor Alpha

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